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DeCS
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Descriptor English:
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Homer Scaffolding Proteins
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Descriptor Spanish:
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Proteínas de Andamiaje Homer
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Descriptor Portuguese:
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Proteínas de Arcabouço Homer
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Synonyms English:
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Homer 1
Homer 1 Proteins
Homer 1C
Homer 1C Proteins
Homer 1a
Homer 2
Homer 2 Proteins
Homer 3
Homer 3 Proteins
Homer Proteins
Proteins, Homer
Proteins, Homer 1
Proteins, Homer 1C
Proteins, Homer 2
Proteins, Homer 3
Proteins, Homer Scaffolding
Scaffolding Proteins, Homer
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Tree Number:
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D12.776.476.024.381
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Definition English:
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Homer proteins belong to a family of adaptor and scaffold proteins which include Homer1, Homer2 and Homer3. Homer1 and Homer2 play a role in the regulation of calcium homeostasis, whereas Homer3 functions in stimulating changes in actin dynamics in neurons and T-cells. Homer proteins are best known as scaffold proteins at the post-synaptic density where they facilitate synaptic signaling. They function as a molecular switch in metabotropic glutamate receptor (MGluR) signaling, and are associated with human Fragile X syndrome. |
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History Note English:
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2017 (1997)
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Allowable Qualifiers English:
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Record Number:
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56636
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Unique Identifier:
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D000072233
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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